Biosynthesis (also called
biogenesis) is an
enzyme-catalyzed process in cells of living
organisms by which
substrates are converted to more complex
products. The biosynthesis process often consists of several enzymatic steps in which the product of one step is used as substrate in the following step. Examples for such multi-step biosynthetic pathways are those for the production of
amino acids,
fatty acids, and
natural products. Biosynthesis plays a major role in all cells, and many dedicated
metabolic routes combined constitute general metabolism.
The prerequisites for biosynthesis are
precursor compounds, chemical energy (such as in the form
ATP), and catalytic
enzymes, which may require reduction equivalents (e.g., in the form of
NADH,
NADPH).
Commonly known complex products of biosynthesis include
proteins,
vitamins, and
antibiotics. Most organic compounds in living organisms are built in biosynthetic pathways.
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